Planter og tradisjon: floraen i levende tale og tradisjon i Norge 1925-1973. rohtoraunioyrtti in Finnish rohtoraunioyrtti in Swedish Bibliographic References common comfrey in English common comfrey in English consolda maggiore in Italian consolda-maior in Portuguese consoude officinale in French consoude officinale in French consound in English consuelda in Spanish consuelda mayor in Spanish echter Beinwell in German gemeiner Beinwell in German gewone smeerwortel in Dutch gewöhnlicher Beinwell in German grande consoude in French healingherb in English knitbone in English okopnik lekarstvennyi in language. boneset in English comfrey in English common comfrey in English common comfrey in language. Common names Arznei-Beinwell in German Beinwell in German Boneset in English Comfrey in English Common Comfrey in English Common comfrey in English Common comfrey in English Common comfrey in English Consound in English Gewöhnlicher Beinwell in German Gewöhnlicher Beinwell in German Gewöhnlicher Beinwell in German Healingherb in English Keihäsnielukukka in Finnish Ketosilmäruoho in Finnish Kjertelaugnetrøst in Norwegian Knitbone in English Læge-kulsukker in Danish Læge-kulsukker in Danish Slippery-Root in English Spids Øjentrøst in Danish Spjutsporre in Swedish Spydbladet Torskemund in Danish Spydtorskemunn in Norwegian Späd ögontröst in Swedish Uddögontröst in Swedish boneset in language. patens (Sibth.) Merrem Symphytum officinale var. glabrescens Nicklès Symphytum officinale var. albiflorum Fuckel Symphytum officinale var. Along with thirty-four other varieties of Symphytum, it is also known as comfrey. Symphytum elatum Tausch Symphytum majus Bubani Symphytum molle Janka Symphytum officinale f. Symphytum officinale is a perpetual flowering plant of the genus Symphytum in the family Boraginaceae. Symphytum commune Faegri Symphytum consolida Gueldenst. Symphytum ambiguum Pau Symphytum coccineum Schltdl. Taxonomic Serial No. All rights reserved.Name Synonyms Consolida major Garsault Consolida major Gilib. Our findings suggest that homoeopathic dose (specially mother tincture) of Symphytum officinale has the potential to enhance osteogenesis.īone healing Gene expression Homoeopathy Mesenchymal stem cells Osteoblasts Osteogenesis Symphytum officinale Traditional medicine Asia & Oceania.Ĭopyright © 2019 Elsevier B.V. Interestingly, gene expression analysis for Runx-2 (n = 10), Osteopontin (n = 10), Osteocalcin (n = 10) and alkaline phosphatase activity (n = 8) also showed increased osteogenesis with the addition of Symphytum officinale to BDM, specially mother tincture. It is a perennial and grows primarily in the temperate biome. Pl.: 136 (1753) This species is accepted The native range of this species is Europe to W. The efficiency of osteogenic differentiation (2 weeks) for different doses of Symphytum officinale was determined by flow cytometry (n = 10) for osteoblast marker, Osteocalcin, and most doses of Symphytum officinale enhanced osteogenesis. Plants of the World Online Kew Science Boraginaceae Symphytum Symphytum officinale L. MTT assay showed that the selected doses of SO did not induce any cytotoxicity in MSCs (24 hours). Gene expression analyses for osteoblast markers (Runx-2, Osteopontin and Osteocalcin) were evaluated in differentiated osteoblasts using qPCR.įlow cytometry (CD90, CD105) detected MSCs isolated from bone marrow (93-98%). Different homoeopathic doses of SO (MT, 3C, 6C, 12C and 30C) were added to the basic differentiation medium (BDM) and efficiency of MSCs differentiating into osteoblasts were measured by evaluating expression of Osteocalcin using flow cytometry, and alkaline phosphatase activity using ELISA. Osteogenic differentiation was induced in MSCs with β-glycerophosphate, ascorbic acid and dexamethasone over 2 weeks. Cytotoxicity of SO was evaluated by MTT assay. MSCs were isolated, expanded and characterized by flow cytometry (CD90, CD105). The medicinal garden Comfrey ( Symphytum officinale ) leaves and roots contain allantoin, which helps the regeneration of new skin cells. Because Symphytum accelerates the formation of a callus (an essential part of the bone repair process), make sure the fracture. It’s used to help healing after a bone fracture has been reset and relieves the pain caused by bone trauma. This study aimed to determine if homoeopathic doses of SO could augment osteogenesis in MSCs as they differentiate into osteoblasts in vitro.īone marrow samples were obtained from patients who underwent bone grafting procedures (n = 15). Symphytum officinale (Comfrey): Used as a poultice, rinse or salve to heal interior and exterior wounds. Homeopathic Symphytum officinale is made from the comfrey root in a way that safely removes the toxicity. Symphytum officinale (SO) is a medicinal plant and in homoeopathic literature, believed to accelerate bone healing. Mesenchymal stem cells (MSCs) are multipotent stem cells possessing regenerative potential.
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